Target Discovery Part 1: DESeq2 — Finding Differentially Expressed Genes from RNA-Seq | Animated
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Target Discovery Part 1: DESeq2 — Finding Differentially Expressed Genes from RNA-Seq | Animated
The starting point of every target discovery campaign. Which genes change between disease and healthy? - The question — 20,000 genes, which ones change between conditions? - Count data — RNA-seq produces integer counts, not continuous values - Negative binomial model — why Poisson isn't enough (overdispersion) - Normalization — median ...
1 month ago
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