Inactivation occurs on a cellular level, resulting in a mosaic expression, in which patches of cells have an inactive maternal X-chromosome, while other patches have an inactive paternal X-chromosome.

In X-inactivation, an X chromosome is compacted (or, as my intro bio professor liked to say, "crumpled up into a ball"), to make a small, dense structure called a Barr body. Most of the genes on the Barr …

2 days ago · Lyonization (also called X-inactivation) refers to the normal phenomenon in which one of the two X chromosomes in every cell of a female individual is inactivated during embryonic …

In particular, by way of the process called X-chromosome inactivation (XCI), female mammals transcriptionally silence one of their two Xs in a complex and highly coordinated manner (Lyon,...

Jun 19, 2025 · X chromosome inactivation (XCI) is a mammalian dosage compensation mechanism that ensures balanced expression of X-linked genes between males and females.

We use the X chromosome inactivation (XCI) paradigm to explore the implication of chromatin changes in gene silencing. Using female mouse embryonic stem cells, we initiate XCI by inducing Xist and …

X-inactivation is a random process that happens separately in individual cells during embryonic development. One cell might shut down the paternal X, while its next-door neighbor might shut down …

Aug 22, 2025 · X-inactivation is a fundamental biological process occurring in female mammals that ensures a balanced expression of genes located on the X chromosome. This process involves the …

Some genes on the X chromosome escape X-inactivation. Many of these genes are located at the ends of each arm of the X chromosome in areas known as the pseudoautosomal regions.

Aug 18, 2023 · Inactivation of the X chromosome, also known as lyonization, occurs randomly, resulting in a unique mosaic of fur coat colors.