Protein phosphatase 1 - Wikipedia
Protein phosphatase 1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. This type of phosphatase includes metal-dependent protein …
Protein Phosphatase 1 - an overview | ScienceDirect Topics
Protein phosphatase 1 belongs to the phosphoprotein phosphatase (PPP) family of phosphatases and is involved in the regulation of a wide variety of cellular processes ranging from …
The phosphatase PP1 sustains global transcription by promoting …
Dec 19, 2024 · Here, we reveal an unexpected role of PP1, within the phosphatase 1 nuclear targeting subunit (PNUTS)-PP1 complex, in sustaining global transcriptional activation in …
Protein phosphatase1 (PP1) - MedChemExpress
Protein phosphatase1 (PP1) is a ubiquitous eukaryotic enzyme that regulates a variety of cellular processes through the dephosphorylation of dozens of substrates.
Emerging roles of the Protein Phosphatase 1 (PP1) in the
Jan 24, 2024 · Protein Phosphatase 1 (PP1) is a major serine/threonine phosphatase in eukaryotes, participating in several cellular processes and metabolic pathways.
Protein phosphatase-1: dual activity regulation by Inhibitor-2
Oct 30, 2020 · It is a small, intrinsically disordered protein that was originally discovered as a potent inhibitor of PP1. However, later investigations also characterized I2 as an activator of …
The phosphatase PP1 sustains global transcription by promoting …
Dec 19, 2024 · However, Wang et al. identify the PP1 phosphatase as a global transcriptional activator that activates pause release by dephosphorylating multiple substrates. They also …
Protein phosphatase 1 in tumorigenesis: is it worth a closer look?
Dec 1, 2020 · Several studies followed, but the role of PP1 in tumorigenesis is still puzzling, with many contradictory findings—which may be one of the causes of PP1 neglect in cancer research.
PDZ-directed substrate recruitment is the primary determinant of ...
May 12, 2025 · Phosphoprotein Phosphatase 1 (PP1) is a member of the PPP superfamily of protein phosphatases, responsible for most cellular serine/threonine dephosphorylation (Bollen …
Role of PP1 in the regulation of Ca cycling in cardiac physiology …
The type 1 protein phosphatase PP1, and the type 2 phosphatases, PP2A and PP2B, constitute the majority of phosphatase activity in the heart. Amongst these enzymes, PP1 is of particular …