Abstract: The subthalamic nucleus (STN) is the primary target for deep brain stimulation (DBS) to treat the motor symptoms of Parkinson's disease (PD). However, the mechanisms of action of STN DBS ...

Deep brain stimulation (DBS) improves motor symptoms of Parkinson's disease by modulating a specific brain network that is mainly active in the fast beta frequency range (20 to 35 Hz). This conclusion ...

The subthalamic nucleus (STN) is a part of the indirect and hyperdirect pathways in the basal ganglia (BG) and has been implicated in movement control, impulsivity, and decision-making. We recently ...

Background Rapid eye movement (REM) sleep behaviour disorder (RBD) is one of the most common sleep problems and represents a key prodromal marker in Parkinson’s disease (PD). It remains unclear ...

Motor function without medication (measured by the Unified Parkinson’s Disease Rating Scale) improved from a mean of 42.8 to 21.1 at year 1 (51%) and 27.6 at year 5 (36%). HealthDay News — Subthalamic ...

The subthalamic nucleus (STN) plays a role in motor control, yet it is unclear whether acute cortical stroke (ACS) causes abnormal STN activity and neural oscillations. Moreover, the correlation ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Nucleus RadioPharma today announced the closing of a Series A extension round with new investor AstraZeneca (LSE/STO/Nasdaq: AZN). Dr. Tyrell Rivers joins the Nucleus Board of Directors ROCHESTER, ...

Background Sleep fragmentation is a persistent problem throughout the course of Parkinson’s disease (PD). However, the related neurophysiological patterns and the underlying mechanisms remained ...

Summary: Deep brain stimulation (DBS) in the subthalamic nucleus, a treatment for Parkinson’s disease, may influence more than just motor control. This treatment, which mitigates Parkinson’s symptoms ...