Non-coding RNA is a ribonucleic acid molecule that is generated from the non-protein coding DNA sequence, that makes up 98-99% of the human genome. A plethora of different types of functional ...

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...

Long non-coding RNAs (lncRNA) are sections of RNA over 200 nucleotides in length that are not translated into proteins, remaining in the nucleus following transcription in relatively low concentration ...

“There is strong debate in the scientific community on whether the thousands of long non-coding RNAs generated from our genomes are functional or simply byproducts of a noisy transcriptional machinery ...

The vast non-coding portion of the human genome has had many names, including ‘junk’ and ‘dark matter.’ But research, including the international ENCODE project, has shown that these regions are ...

Researchers from Duke Health and the University of Minnesota recently discovered that measuring specific tiny genetic ...

Much of our early work focused on the MALAT1 locus, which is over-expressed in many human cancers and produces a long nuclear-retained noncoding RNA as well as a tRNA-like small RNA known as mascRNA, ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Non-coding RNAs and oxidative stress work together in various stages of cancer progression, including cancer cell growth and reproduction, cancer cell invasion, tumor microenvironment shaping, ...

Scientists have identified an RNA-based sperm aging clock driven by rsRNA length changes, which may help assess paternal reproductive risk and offspring health.