Scientists have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off. The findings shed light on the processes that lead to the ...
The ability of a human body to resist pathogenic factors is under control of immune cells, the most important of which are lymphocytes. The first subtype called effector lymphocytes, contacts with ...
The thymus prevents autoimmunity by inducing apoptosis of the T cells that express autoreactive receptors to self peptides. But this mechanism alone is insufficient and CD4+CD25+ regulatory T cells ...
San Diego, CA, USA, and Munich, Germany – October 21, 2025 – selectION, Inc. (“selectION” or the “Company”), a clinical-stage biopharmaceutical company developing novel treatments for T cell-mediated ...
The unique role of citrullination in osteoclast differentiation and ACPA-induced osteoclast activation might explain important features of the gradual development of rheumatoid arthritis, including ...
Scientists at Helmholtz Zentrum München have discovered a mechanism that amplifies the autoimmune reaction in an early stage of pancreatic islet autoimmunity prior to the progression to clinical type ...
Scientists have discovered a mechanism that amplifies the autoimmune reaction in an early stage of pancreatic islet autoimmunity prior to the progression to clinical type 1 diabetes. If the ...
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