Meteorologists said there was a chance the winds would be as severe as those that fueled the Palisades and Eaton fires, but that different locations would likely be affected.
With the strongest gusts expected on Tuesday, extreme fire condition threats will prevail until midweek, L.A.-area fire chiefs say.
The National Weather Service issued a Red Flag Warning starting Monday for San Diego County's inland valleys and mountains.
The latest Santa Ana winds will return Monday, with the strongest gusts expected Monday night into Tuesday morning, as Los Angeles fires continue to burn.
The ferocious Santa Ana winds that helped fuel the deadly wildfires around Los Angeles are forecast to ease later Wednesday, but they may return.
A "Particularly Dangerous Situation" warning remains in effect as strong winds cause extreme fire danger in Southern California.
After a brief break on Sunday afternoon, another prolonged round of gusty Santa Ana winds is expected to develop, forecasters say.
Officials warn the peak of the Santa Ana winds have been pushed back by about a day from the original timeline.
The potentially hazardous conditions are expected Tuesday afternoon through Wednesday in Los Angeles and Ventura counties, according to the NWS.
Another wave of Santa Ana winds arrive Saturday, likely generating gusts over 40 mph throughout the Inland Empire going into Sunday.
National Weather Service offices across Southern California are warning residents of an increase in weather conditions that are conducive to rapid fire growth. Meteorologists are most concerned about conditions from Monday afternoon through Wednesday morning when winds will be at their peak and relative humidity will be low.
Powerful Santa Ana winds are returning to the Los Angeles area this week, worrying officials as they work to contain multiple large wildfires.