How T cells transform to defend our organs

There are many kinds of T cells, and they play different parts in defending the body. Some T cells kill infected cells, ...
Hosted on MSN

Discovery of CAR-T 'memory cells' could boost cancer therapy

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with ...
Frontiers

Tissue‑immune crosstalk: Mechanisms and implications for T cell function and homeostasis

The field of tissue-immune interactions has undergone significant transformation as emerging evidence demonstrates the centrality of local microenvironments ...
The Scientist

Beyond Cytotoxicity: The Importance of T Cell Memory

B cells are the classical shield bearers of immune system memory, but memory T cell phenotypes also exist, playing crucial roles in controlling viral infections and modulating immune responses. In ...

From blood to solid tumors: A new way to power up CAR T cell therapy

T cell therapies have revolutionized cancer treatment—but so far, their success has been largely limited to blood cancers. Solid tumors, which account for around 90% of all adult cancers, remain a ...
Technology Networks

CRISPR-Enhanced CAR T Cells Overcome Solid Tumor Barriers

Monash University researchers used CRISPR or a PTPN2 inhibitor to enhance CAR T cell function against solid tumors. Blocking ...
Fred Hutch

CD27 - the key to long-term responses for CAR-T cell therapy?

Chimeric Antigen Receptor T (CAR-T) cell therapy is a new type of cancer treatment that has shown great promise in treating blood cancers, such as B cell lymphomas and leukemias, and multiple myeloma.