Intrinsically disordered proteins (IDP) are proteins that lack tertiary structure. They are now being recognized as biologically crucial in both healthy systems and the pathophysiology of various ...

As the importance and prevalence of oligonucleotide therapeutics continue to grow, so does the need for robust characterization methodologies throughout drug development and production. Given the ...

Fluorinated compounds are increasingly used in medicinal, agricultural, and material science applications. NMR probes and procedures were historically employed to get hydrogen and carbon spectra.

image: A novel NMR technique developed at U of T Scarborough has the potential for noninvasive disease diagnosis using current MRI technology. view more A novel technique developed by University of ...

Nuclear magnetic resonance (NMR) is an information-rich technique. However, it requires a higher analyte concentration than all other spectroscopic methods, especially when compared to analytical ...

In conventional NMR, a sample is placed in an external magnetic field, which aligns the spins of any nuclei with magnetic moments in the sample. Radio-frequency (RF) pulses are then sent into the ...

When working a cold case, smart investigators try something new. By taking a novel approach to nuclear magnetic resonance spectroscopy — a blending of four techniques — scientists have been able to ...

In this editorial, Enrico Ravera gives an overview of the use of paramagnetic metals in NMR and explains how this can provide crucial information about the structure and dynamics of proteins, nucleic ...

Nuclear magnetic resonance (NMR) spectroscopy could be about to go mobile, thanks to a team of researchers in the US that has shrunk the electronic components needed for the spectroscopic technique ...