Immunologists have identified a previously unrecognized group of immune cells that could reshape how vaccines and immune-based therapies are designed. The newly described cells 1 are long-lived memory ...

Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve ...

CD4+ T-cells, primarily considered to play a supportive role in the anti-tumor immune response, have been seen to actively kill cancer cells in a mouse model of melanoma. A recent study by a team at ...

New research from Memorial Sloan Kettering Cancer Center (MSK) finds the TCA cycle’s waste-management function may present an ...

Findings suggest engineered CD4+ T cells can modify Alzheimer's pathology and improve CNS immune responses, highlighting a ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the ...

T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause ...

During infections, the immune system needs to distinguish foreign molecules from invading bacteria and viruses from molecules that are made by cells of the body. If it can’t, the immune system can ...