Ubiquitination is a crucial post-translational modification process where the small protein ubiquitin is attached to target proteins, marking them for degradation or altering their function. This ...

Transverse tubules (T-tubules) play a significant role in muscle contraction. However, the underlying mechanism of their formation is yet to be elucidated. In a recent study, a research team from ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

Mechanisms associated with the genesis of cancer stem cell stemness, such as oxidative stress, tumor metastasis and recurrence, hypoxia induction, and tumor invasion. Genes & Diseases publishes ...

Although most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals experience mild symptoms, some contract a severe infection that affects multiple organs in the acute ...

Ubiquitin is a small protein consisting of 76 amino acids that binds to lysine residues of substrates, usually by a combination of three enzymes: a ubiquitin-activating enzyme (E1, two types), a ...