A small-molecule ligand that binds to a (CAG) n hairpin repeat is the basis of a biosensor to detect repeat length, which may help diagnose trinucleotide repeat disease severity. DNA trinucleotide ...
CAG and CTG (CWG) trinucleotide repeat expansions cause various neurological diseases, which can be classified as polyglutamate (polyQ) disorders (such as Huntington disease (HD)) with abnormal CAG ...
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