Individuals with β-thalassemia develop progressive systemic iron overload, resulting in high morbidity and mortality. These complications are caused by labile plasma iron, which is taken up by ...

Incorporating structural constraints into pharmacokinetic studies of iron sucrose formulations. Results from assays conducted independently of one another can produce findings that are incompatible ...

Low iron saturation occurs when the amount of iron in the blood decreases below the recommended range. Measuring transferrin is one way to determine iron saturation. Iron saturation refers to the ...

A new study led by researchers at the Graduate Entry Medical School (GEMS), University of Limerick (UL) has found that people with low levels and very high levels of a commonly measured laboratory ...

What Is a TIBC Blood Test? A total iron-binding capacity test is a blood test that tells you how much iron is binding to the transferrin in your blood, which tells you how well iron is functioning in ...

The blood brain barrier (BBB) exists to protect the brain from pathogens and other toxins but makes central nervous system (CNS) diseases hard to treat with conventional drugs. For example, many ...

Medizinische Universitätsklinik Freiburg, Abteilung Rehabilitative und Präventive Sportmedizin, Hugstetter Str 55, 79106 Freiburg, Germany Correspondence to: Dr Schumacher, Abtlg RP Sportmedizin, ...

Transferrin's Fe 3+-binding site grips the metal (small orange ball) with a carbonate anion, two tyrosinates, an aspartate, and a histidine. Credit: Howard Lightfoot and Arindam Mukherjee Transferrin, ...