For decades, losing a permanent tooth has been considered irreversible. Once a tooth was gone, the only solutions were ...

The interaction between Hertwig's epithelial root sheath (HERS) and surrounding mesenchymal cells is crucial for root dentin formation. HERS influences tooth root development and odontoblast ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

Teeth function not only because of the hard enamel on the surface, but also because they have roots that anchor them firmly in the jawbone beneath the gums. Eating, speaking, and maintaining the shape ...

Two distinct stem cell lineages that drive tooth root and alveolar bone formation have been identified by researchers from Science Tokyo. Using genetically modified mice and lineage-tracing techniques ...

A novel study on the natural coordination of tooth development in time and space, led by Dr. Han-Sung Jung at the Yonsei University College of Dentistry, Korea, has discovered that "lingual" cells on ...

Sometimes, a tooth can become so severely damaged or infected that your dentist might discuss a couple of different kinds of treatment plans with you. The first is a root canal, and the other is a ...

Schematic diagram illustrating how Gli2 and Gli3 regulate Acvr2b-mediated TGF-β/SMAD signaling to control proliferation and differentiation of dental mesenchymal progenitor cells during tooth root ...

Lizzie Duszynski-Goodman is a journalist living in the Midwest with her husband and two young children. Her work explores the intersection of mental health, wellness and parenting. She is the former ...

Root canal treatment is designed to save a natural tooth by removing infected pulp, not to cause pain. An infected tooth, often causing severe tooth pain or sensitivity, can lead to bone loss or ...