T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged ...

Immunotherapies – treatments that aim to make the body's natural immune system more effective – are becoming more widely used ...

A new stem-cell-inspired technique allows scientists to grow vast numbers of immune-cell progenitors that can be engineered ...

Summary: Chimeric Antigen Receptor T-cell (CAR-T) therapy has revolutionized the treatment of liquid blood cancers by engineering a patient’s own immune cells to destroy malignant targets, replicating ...

Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill ...

Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two ...

Researchers say approach could be useful for both initial treatment of bladder cancer as well as treatment refractory subsets of tumors.

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...

The first clinical trial to test the tumour-fighting power of a stem-cell-like class of long-lived immune cells suggests that they could be more potent and less toxic than the standard mix of cells ...

Adults with blood cancers who receive stem cell transplants from matched donors now have a new defense against one of the ...