Dispatch Bio, a biotech company engineering a universal treatment across solid tumors leveraging its first-in-class Flare ...

The orchestration of T cell activation is central to immune defence and self-tolerance. Recent advances have revealed that T cells integrate signals from their antigen receptors alongside a network of ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

CD8+ T cells divide cysteine between pathways that control growth and cancer-killing activity. Adjusting its use can enhance ...

A study shows mitochondrial electron flow keeps dendritic cells primed, regulating gene activity and T-cell activation. The ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

A protein that helps cancer cells hide from the immune system may have a critical weakness, according to research that could ...

While modern life includes many conveniences, humans are still incessantly exposed to a variety of metabolic stresses we have ...

A detailed analysis of T-cell redirecting therapies in oncology, comparing the mechanisms of bispecific antibodies and CAR T ...