Molecularly targeted therapies are increasingly relevant in clinical oncology, as they enable the selective modulation of specific biologic targets—such as enzymes or receptors—by inhibiting or ...

A comprehensive new systematic review published in The Journal of Nutrition provides the latest evidence that large-scale food fortification is a highly cost-effective intervention for reducing global ...

Data sources Six databases, six trial registries and prior systematic reviews. Forward and backward citation tracking was employed. Eligibility criteria Randomised controlled trials that compared ...

Data sources Five online databases (PubMed, CINAHL, PsychInfo, SportDiscus and Web of Science) searched from inception through 14 September 2023. Hand-searches and contacting authors for eligible ...

This systematic review found that studies of case management interventions have adequate quality and, in many cases, show cost-effective or even cost-saving results. Results: A total of 29 studies ...

Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor Five databases and two registries were searched for randomized controlled trials or ...

Digital Health Interventions to Promote Physical Activity Among Adolescents: Systema ...

A comprehensive database search was performed for full-text, English-language articles published from January 1, 2000, to December 31, 2022. Included studies compared survival between Black and White ...

A new publication in Nature Reviews Methods Primers provides essential guidance for conducting rigorous systematic reviews on studies with animals and cells. It also highlights the benefits of these ...