Scientists at deCODE genetics and collaborators have published a study in the Journal of Allergy and Clinical Immunology reporting a rare missense variant in STAT6 that protects against asthma. Asthma ...

Please provide your email address to receive an email when new articles are posted on . The STAT5 and STAT6 transcription factors activate Th9 cells. Th9 cells produce the IL-9 cytokine, which causes ...

Kymera Therapeutics, Inc. KYMR announced that its investigational New Drug (IND) application for pipeline candidate, KT-621, has been cleared by the FDA. KT-621 is an investigational first-in-class ...

REX-8756 is a potent and selective oral STAT6 inhibitor that has shown complete 100% pathway inhibition and potent efficacy in preclinical models of asthma, acute lung inflammation and dermatitis ...

In a separate financing round, Pandorum Technologies announced the close of an $18 million Series B financing to support the ...

Signal transducer and activator of transcription 6 (STAT6) is a member of the STAT family involved in the regulation of immune response and inflammation. The development of SH2 domain inhibitors ...

Gilead Sciences’ inflammation drug prospects have come via deals, and the latest one brings drug candidates for an elusive target that’s in pursuit by a growing number of companies. The drugmaker is ...

Nurix Therapeutics secures a $15 million license extension from Sanofi for its STAT6 program, totaling $127 million to date. Nurix Therapeutics announced that Sanofi has exercised its option to ...

Kymera Therapeutics, Inc. (NASDAQ:KYMR) on Monday revealed clinical results from the Phase 1 healthy volunteer study of KT-621, its first-in-class, oral STAT6 degrader medicine. The findings ...

Codiak BioSciences, Inc., a clinical-stage biopharmaceutical company pioneering the development of exosome-based therapeutics as a new class of medicines, today announced the online publication of a ...

Efferocytosis of apoptotic neutrophils (PMNs) by alveolar macrophages (AMΦs) is vital for resolution of inflammation and tissue injury. Here, we investigated the role of AMΦ polarization and ...