Activating two somatostatin receptors enhances amyloid beta breakdown and improves memory in models of Alzheimer’s disease. Scientists at Karolinska Institutet in Sweden and the RIKEN Center for Brain ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Researchers at Karolinska Institutet have identified small molecules capable of influencing a hard-to-target receptor family ...

Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...

Up-to-date computational pipeline characterizes G-protein-coupled receptor (GPCR) repertoires in the closest relatives of metazoans, providing a framework to investigate the evolutionary origins and ...

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...

T cell immunotherapies are on the cutting-edge of cancer treatments, but a full understanding of how they work has been ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...

For decades, depression treatment has focused almost entirely on the brain, with drugs designed to tweak neurotransmitters ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...