Ribosomal engineering creates 'super-probiotic' bacteria with enhanced immune activation

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
Science Daily

First mouse model with mitochondrial tRNALeu mutation developed

Researchers have developed the first mouse model for a mitochondrial tRNALeu mutation, showing that the associated metabolic disorder results from faulty RNA processing. Studying the role of ...
News Medical

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the ...
Science Daily

Why synonymous mutations are not always silent

New modeling shows how synonymous mutations -- those that change the DNA sequence of a gene but not the sequence of the encoded protein -- can still impact protein production and function. New ...
EurekAlert!

First mouse model with mitochondrial tRNALeu mutation developed

Tsukuba, Japan—Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models ...