The bacterial chaperonin complex — consisting of the proteins GroEL and GroES — assists the folding of newly synthesized proteins by transiently encapsulating them in a nanometre-scale cage.
Proteins and peptides form the cornerstone of cellular function, serving not only as essential catalysts and structural components but also as mediators of signalling and regulation in health and ...
Protein folding raises some of biology's greatest theoretical challenges. It also lies at the root of many diseases. For example, the fundamental question of whether a protein's final tertiary ...
Demis Hassabis (CEO of Deep Mind) and John M. Jumper have useed artificial intelligence to predict the structure of almost all known proteins. David Baker has learned how to master life’s building ...
Scientists have discovered the first evidence of protein folding driven by liquid-liquid phase separation, a phenomenon in which fluids form into microscopic droplets and separate inside cells -- like ...
Hebert (center) and lead author, Guay (3 rd from left) with members of Hebert’s research group. From left, Haiping Ke, Robert Williams, Guay, Hebert, Liza Pobezinskaya, Gracie George and Wen-chuan ...
Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the ...
June 10, 2025 — IUSB Professor of Biochemistry Shahir Rizk talks about his new book about proteins, what they do for us, and how. To learn more about the amazing people in our communities, stay tuned ...
Matthew D. Shoulders, a leading figure in protein biochemistry and synthetic biology, has been appointed head of the Department of Chemistry at the Massachusetts Institute of Technology (MIT), ...
is a senior reporter who has covered AI, robotics, and more for eight years at The Verge. AI research lab DeepMind has created the most comprehensive map of human proteins to date using artificial ...
David Baker has long been at the forefront of AI-driven protein folding and now protein design, and his lab continues to make huge leaps forward while pushing for a culture of transparency in its ...
A multicolored protein structure is blurred at the edges and comes into focus toward the center. Detail of a protein designed using a tool called ProteinMPNN Credit: Ian C. Haydon/UW Institute for ...