A protein that appears in postsynaptic protein agglomerations has been found to be crucial to their formation. The Kobe University discovery identifies a new key player for synaptic function and sheds ...

Endogenous cannabinoids, also known as endocannabinoids, are neurotransmitters (i.e., chemical messengers naturally produced by the body) that transmit specific signals from one neuron to another.

Neurons send signals to each other across small junctions called synapses. Some of these signals involve the flow of potassium, calcium and sodium ions through channel proteins that are embedded ...

Long-lasting changes in synaptic function are thought to be the cellular basis for learning and memory and for activity-dependent plasticity during development. Most of the work on synaptic plasticity ...

Long-term depression (LTD) between cortical layer 4 spiny stellate cells and layer 2/3 pyramidal cells requires the activation of NMDA receptors (NMDARs). In young rodents, this form of LTD has been ...

Synaptic plasticity describes the biological process that enables learning and memory through facilitating changes in the connections between synapses. Interaction with the external world results in ...