Researchers have discovered that activating the pentose phosphate pathway makes antitumor CD8+ T cells more likely to stay in an immature, stem-like, “precursor” state. Combining this metabolic ...
(a) Proposed protometabolic pentose pathway leading to the accumulation of aldonates followed by nonselective oxidation to uronates, carbonyl migration, and β-decarboxylation. (b) First few steps of ...
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