A lithographic (litho) hotspot is a defect on a wafer that is created during manufacturing by a combination of systematic process variation and resolution enhancement technology (RET) limitations.

Choudhury, Prithwiraj, Ryan Allen, and Michael G. Endres. "Machine Learning for Pattern Discovery in Management Research." Strategic Management Journal 42, no. 1 (January 2021): 30–57.

There's a lot of loose talk about our AI-driven future. But expect to keep using your own brain for a long time to come Artificial intelligence — in the guises of personal assistants, bots, ...