This important study combines optogenetic manipulations and wide-field imaging to show that the retrosplenial cortex controls behavioral responses to whisker deflection in a context-dependent manner.

Light can trigger a signaling cascade in the cerebellum. This also illuminates processes that play an important role in cerebellar diseases. Processes in the cerebellum are involved in various ...

Scientists at Scripps Research Institute have created a groundbreaking method to track when brain cell activity decreases or switches off after a burst of activity using a combination of optogenetics ...

Using light stimulation and MRI, scientists compared the effects of stimulating the brain’s serotonin center in awake and anesthetized mice, showing a clear difference in activation levels between the ...

Optogenetic climbing fiber activation regulates experience-dependent plasticity in the primary somatosensory cortex of mice, suggesting a role of the olivo-cerebellum in instructive signaling across ...