In a letter to the FDA, the American Society of Anesthesiologists has addressed public health concerns associated with the use of equianalgesic opioid conversion tables and has recommended a staged ...

The FDA is conducting a workshop to discuss the science (lack thereof, really) of Morphine Milligram Equivalents as it applies to the atrocious CDC 2016 Opioid Prescribing Guidelines. Public comments ...

Drug overdose deaths, once rare, are now the leading cause of accidental death in the U.S., surpassing peak annual deaths caused by motor vehicle accidents, guns and HIV infection. As a former public ...

Opioids are frequently overprescribed after surgery. We applied a tabular foundation model to predict the risk of post-discharge opioid consumption. The model was trained and internally validated on ...

Categories were determined on the basis of the codes of the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, that were obtained from death records.

Opioid agonist therapy is strongly recommended for pregnant persons with opioid use disorder. Buprenorphine may be associated with more favorable neonatal and maternal outcomes than methadone, but ...

A variety of psychological processes are thought to be modulated by the brain’s mu-opioid system, including reward [1], pain [2], stress [3], and social bonding [4, 5]. A popular method to study the ...

Medical utilization profiles of commercially insured members with opioid-related disorders differ depending on the code used to document the initial diagnosis in administrative claims. Results: A ...