Figure 1: Nondisjunction causes near-diploid aneuploidy, not cytokinesis failure, in primary cells. If nondisjunction were to give rise to binucleation and if binucleate cells were to survive as well ...

Figure 1: Chromosome mis-segregation occurs at high frequency in spontaneously arising binucleated cells. Figure 2: Nondisjunction occurs with high frequency in cells that become binucleated by furrow ...

Methods have been developed in the past to assess spontaneous and induced chromosomal aneuploidy in germ cells and in early pre- and postimplantation mammalian embryos. Some of these methods yield ...

Changes in either chromosome structure or number can occur during cell division. Each human has 46 chromosomes, 22 pairs of autosomes and 1 pair of sex chromosomes (XX: female or XY: male). During ...

Chromosome nondisjunction lands a heavy blow on the chin of humanity. The improper segregation of chromosomes during meiosis leads to chromosomally unbalanced eggs or sperm. If these gametes ...