NRG5051 is a first-in-class, orally bioavailable and CNS-penetrant next-generation inhibitor of the mitochondrial permeability transition pore (mPTP), acting through a novel undisclosed ...

While Alzheimer's Disease is traditionally associated with the buildup of plaques, emerging evidence suggests that mitochondrial dysfunction may play a role in the onset and progression of this ...

Stevenage, United Kingdom Saturday, January 10, 2026, 14:00 Hrs [IST] ...

Central to the dysfunction is the aberrant modification of mitochondrial enzymes by S-nitrosylation, a chemical reaction where nitrogen and oxygen atoms bind to sulfur atoms on proteins. This ...

Neuronal intranuclear inclusion disease (NIID) is a neuromuscular/neurodegenerative disease caused by the expansion of CGG repeats in the 5′ untranslated region ...

Researchers have discovered two proteins that act as regulators for mitophagy. The discovery opens a new avenue for researchers to boost mitophagy activity, to promote mitochondrial and neuronal ...

A new study reveals that nerve cells receive periodic infusions of mitochondria from neighboring cells — and this may point ...

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...

Tisento Therapeutics today announced that the global Phase 2b PRIZM study is fully enrolled. PRIZM is evaluating zagociguat – a once-daily, oral investigational medicine – as a treatment for the rare ...