Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is an urgent need for effective and targeted therapies that can improve ...

Cells have surface receptors that couple with proteins and other molecules to initiate or inhibit certain behaviors.

Neuronal differentiation and maturation are crucial for developing research models and therapeutic applications. Brain-derived neurotrophic factor (BDNF) is a widely used biochemical stimulus for ...

Combining microscopy, scanning, and deep learning enables more precise imaging of functional dynamics in neural networks of human cortical organoids.

The functional complexity and anatomical organization of the nervous system are established during regional patterning of its embryonic precursor—the neural tube. Human pluripotent stem (hPS) ...

Researchers discover that the GPR3 receptor acts as an immediate-early gene to jumpstart neuron and synapse development.

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are ...

The brain's mechanisms for repairing injuries caused by trauma or degenerative diseases are not yet known in detail. Now, a study by the University of Barcelona describes a new strategy based on stem ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

New study by Chiba University, Japan in collaboration with Karolinska Institutet, Sweden, uncovers novel enhancer-promoter interactions that regulate gene expression during neuronal differentiation ...