As knowledge of the development of neuronal pathways continues to grow, it also elucidates potential treatment modalities for neuronal degenerative diseases and injuries. Molecular and genetic ...

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...

Lysosomes regulate cellular metabolism to maintain cell survival, but the mechanisms whereby they determine neuronal cell fate after acute metabolic stress are unknown. Neuron-enriched lysosomal ...

Scientists tracking blind Mexican cavefish uncover a striking evolutionary reversal where existing brain circuits are rewired via dopamine to flip behavioral responses to light.

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

The ability to regulate one's own food intake is essential to the survival of both humans and other animals. This innate ability ensures that the body receives the nutrients it needs to perform daily ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

The nervous system is primarily composed of neurons and glia, and the communication between them has profound roles in regulating the development and function of the brain. Neuron–glia signal ...

Scientists have uncovered the intricate circuit cues behind neuronal cell maturation and migration, which is required for proper cognitive function. The journey of a thousand miles begins with a ...

Overview of the study. Researchers investigated the neural basis of how animals adapt to new environments and situations. To do this, they introduced a chemical ON/OFF switch in the orbitofrontal ...