Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic protein signaling in the developing spinal cord.

Netrin1 is a protein that was first characterized for its axon guidance activities during embryonic development. The netrin family has been shown to play many critical roles in developmental and ...

Spinal cord injury (SCI) causes structural damage to neural circuits, which in turn leads to sensory and motor dysfunction. Transplantation of neural precursor cells/stem cells provides a potential ...

Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning. St. Jude Children's Research Hospital ...

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal ...