Nerandomilast's tolerability and dual antifibrotic/immunomodulatory mechanism directly address the critical non-adherence ...

But the mechanism of action of a major monoclonal antibody developed for ulcerative colitis has remained elusive—until now. The antibody is known as vedolizumab (VDZ) and it is prescribed under the ...

The lead Neumora Therapeutics, Inc. product candidate, Navacaprent, has shown promise in treating major depressive disorder, MDD, and bipolar depression. The lead product candidate, Navacaprent, is a ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...

HONOLULU — Glovadalen (UCB), an investigational brain-penetrant D1 receptor positive allosteric modulator (D1 PAM), is both safe and effective for patients with advanced Parkinson’s disease (PD), new ...

Evaluation of the PI3K inhibitor BAY 80-6946 in hematologic malignancies. ERCC1, p16, and Ki-67 immunohistochemichal expression as predictive and prognostic markers in head and neck squamous cell ...

Toxicity results and early outcome data on a randomized phase II study of docetaxel ± bevacizumab for locally advanced, unresectable breast cancer ...

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Several small biotechs working on new treatments for weight loss believe that developing therapies with mechanisms of action not seen with current drugs, such as those from Novo Nordisk (NVO) and Eli ...

In a recent pioneering study, researchers at Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven ...