Microscopy image showing activated hepatic stellate cells (HSCs), indicated by red staining (left image). Inhibition of CYB1B1 reduces HSC activation (right image), which leads to reduced liver ...

Increased miR-34a induced by obesity and high-fat diet enhances hepatic de novo lipogenesis and disturbs biosynthesis of very-low density lipoprotein metabolism via down-regulation of Mttp, ApoB, and ...

Liver fibrosis may be diagnosed and staged — no fibrosis (stage F0), mild fibrosis (F1), significant fibrosis (F2), advanced fibrosis (F3), and cirrhosis (F4) — with the use of clinical parameters and ...

Chronic liver disease, a growing threat to global health, often progresses silently in its early stages. Detecting its precursor, steatotic liver disease (SLD), and advanced liver fibrosis before ...

A study reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic ...

Jay N. Yepuri, MD, MS, FACG, is a board-certified gastroenterologist and member of the Digestive Health Associates of Texas Board of Directors and Executive Committee. Liver fibrosis is scarring that ...