Could people with Type 1 diabetes one day replace insulin with leptin? A research team at UT Southwestern has had promising results with animal studies and now is laying the groundwork for testing it ...

Leptin, a protein secreted by fat cells, may be an independent risk factor for heart disease in humans, according to an article in Circulation: Journal of the American Heart Association. Leptin, a ...

Obesity is often a combination of genetic and lifestyle factors. Genetics can influence metabolic pathways, appetite control, and energy storage. Leptin resistance can lead to increased appetite and ...

Cocaine is habit-forming because of its ability to enhance dopaminergic neurotransmission in the forebrain. In addition to neuronal inputs, forebrain dopamine circuits are modulated by hormonal ...

Many Americans, especially women, are obese but mistakenly think they’re at a healthy weight because of major flaws in the body-mass-index formula, say the authors of a new study. An analysis ...