A significant overlap has been identified in the functionalities of genes associated with immune and metabolic disorders, suggesting a fundamental frameshift is needed in our understanding of the two.

A hidden immune cascade linking the gut and bone marrow may explain how IBD turns inflammation into colon cancer.

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

Scientists have long observed that cancer patients have a lower risk of Alzheimer’s disease. New research reveals a possible ...

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...

The deal underscores a broader shift in autoimmune drug development toward therapies that aim to reprogram disease-driving ...

Bacteria in the human gut can directly deliver proteins into human cells, actively shaping immune responses. A consortium led ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients ...

Researchers used health administrative data from the province of Ontario, Canada, to assess the association between immune-mediated GI disease and the subsequent development of an eating disorder in ...

Other than the telltale signs of weight changes, shifts in gut functions or the immune system may also indicate underlying ...