Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...

Glioblastoma is the most common form of brain cancer in adults, and its consequences are usually quick and fatal. After receiving standard-of-care treatment (surgery followed by radiation and ...

“This review explores our current understanding of how ECM geometry influences the behaviors of both immune cells and tumor cells, which in turn impacts treatment efficacy and cancer evolutionary ...

Underinvested, Under-Referred, and Underserved: Applying a Gender Equity Continuum Framework in Cancer Control Continuum Programs and Policies to Expand to Transgender and Nonbinary Populations ...

Bio X Cell has announced the launch of the first commercially available ready-to-use anti-mouse PD-L1 × TIGIT × LAG3 trispecific antibody, introducing a new approach to studying combinatorial ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that engulf pathogens and cancer cells—can be used to predict whether or not a ...