Scientists have uncovered evidence supporting a mechanism in which transposable elements (TEs), once considered ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three ...

Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like ...

The University of California, Santa Cruz, has played a key role in an international project to catalog all of the biologically functional elements in 1 percent of the human genome. The results of the ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still ...

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still ...

Life depends on genes being switched on and off at exactly the right time. Even the simplest living organisms do this, but usually over short distances across the DNA sequence, with the on/off switch ...