Once disregarded as “junk DNA,” scientists now know that this molecular dark matter is crucial for determining gene activity ...

Epigenome editing has followed a similar path, in that more recent technological breakthroughs have enabled scientists to apply the discoveries made in previous decades. Epigenome editing performs a ...

It could transform our understanding of why diseases develop and the medicines needed to treat them, says researchers.

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...

Scientist suggests viewing genetic code not as a static "manual" that determines how organisms function, but a dynamic process of the birth of meaning and signs—semiosis. As part of this approach, the ...

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...

Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...

Major depression is not only a crisis of mood, it is also a crisis of biology that reshapes the brain itself. As genetic ...

DeepMind’s AlphaGenome AI model could help solve the problem of predicting how variations in noncoding DNA shape gene ...

Researchers reckon it could dramatically accelerate understanding of how DNA influences disease, cancer, and drug discovery.