Actions are not mediated solely by cortical processes but rely on communication within basal ganglia-thalamocortical loops. Speech is one example, although how the basal ganglia participate in this ...

Although dystonias are a common group of movement disorders, the mechanisms by which brain dysfunction results in dystonia are not understood. Rapid-onset Dystonia-Parkinsonism (RDP) is a hereditary ...

The subthalamic nucleus (STN) and external globus pallidus (GP) form a recurrent excitatory-inhibitory interaction within the basal ganglia. Through a computational model of these interactions we show ...

A brain imaging study showed differences in the basal ganglia when chronic fatigue syndrome patients (CFS) vs. healthy controls played a card game. The findings suggest that chronic fatigue syndrome ...

Neurons deep in the brain not only help to initiate movement—they also actively suppress it, and with astonishing precision. This is the conclusion of a new study by researchers at the University of ...

Neurons deep in the brain not only help to initiate movement -- they also actively suppress it, and with astonishing precision. The findings are especially relevant for better understanding ...

Researchers at Karolinska Institutet, Columbia University and the University of San Francisco, have uncovered a previously unknown mechanism by which dopamine, a key brain chemical vital for movement ...