In the realm of biological sciences, bile acids stand as pivotal molecules, playing a multifaceted role in various physiological processes within organisms. Bile acids are specialized molecules ...

Hepatic synthesis of bile acids is the primary pathway for cholesterol catabolism. The cholesterol 7α-hydroxylase enzyme (encoded by CYP7A1) represents the rate-limiting step of the multi-enzymatic ...

The discovery of dedicated bile acid receptors and further research defined multiple bile acid signalling routes affecting bile acid synthesis, lipid synthesis, gluconeogenesis, inflammation, liver ...

Examining gut health from a different angle, Flinders University’s Associate Professor Robyn Meech is looking at what can trigger colon cancer – and she believes bile acids may provide a significant ...

A new study presented today at the International Liver Congress™ 2012 demonstrates that the gut microbiota has a profound systemic effect on bile acid metabolism.(1) Bile acids are synthesised from ...

Researchers have identified a new axis of host defense by studying what happens during enteric infection -- a term that encompasses all types of intestinal infections including so called 'stomach flu.

The gut microbiota have a known role in modulating gut immune homeostasis. Largely, through the development and function of host immune cells, including T helper cells expressing interleukin-17A. It ...

Researchers have identified a new axis of host defense by studying what happens during enteric infection—a term that encompasses all types of intestinal infections including so called “stomach flu.” A ...

"Enlarged bile ducts or dilated bile ducts are typically caused by a biliary tree obstruction, which can be caused by stones, tumours (usually of the papilla of Vater or the pancreas), benign ...

What Is Bile Duct Cancer? Bile duct cancer, also called cholangiocarcinoma, is when unusual cells grow out of control inside your bile ducts. Those are thin tubes about 4 to 5 inches long that move a ...

Bile duct cancer is rare, but it may be fatal. A person’s outlook will depend on the location of the cancer and the stage of the disease when they receive a diagnosis. In this article, we discuss the ...

Bile duct cancer, also known as cholangiocarcinoma, is a rare form of cancer that affects the bile ducts. Two bile ducts in the human body connect the liver and gallbladder to the small intestine.