Microvascular endothelial dysfunction is an early or inductive event that occurs in the development of cardiovascular diseases and associated organ damage. The endothelium is composed of a single ...

Heart disease often begins silently with endothelial dysfunction, a subtle weakening of blood vessel linings. This early ...

The endothelium is a cell layer that lines the body’s blood vessels and lymphatic vessels. These cells are necessary to maintain healthy organs, tissues, and overall body function. The cells of the ...

Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...

The glycocalyx emerges as an active endothelial system whose structure, metabolism, and shear-dependent regulation integrate mechanical forces with vascular signaling. Disruption of this system ...