Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a protein and alter its function. A team at HZB has now investigated the Nsp1 ...

The GPCRact AI model goes beyond AlphaFold3 by predicting whether drugs functionally activate G-protein-coupled receptors through allosteric signaling.

A new computer process makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process could revolutionize drug ...

Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers at Brown University has developed a way ...

A recently identified bacterial protein, named BeeR, is contributing to the design of novel anticancer drug delivery systems. Researchers from King’s College London (UK) and the University of ...

Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for ...

Researchers at Nano Life Science Institute (WPI-NanoLSI) and the Cancer Research Institute at Kanazawa University have uncovered how targeted lung cancer drugs alter the shape and behavior of a key ...

Nuclera, the biotechnology company enabling rapid access to high-quality proteins and leadXpro, a specialist in structure-based drug discovery for membrane proteins, today announced a scientific ...

When new medicines are invented, the drug may hit the intended target and nullify the symptoms, but nailing a bull's eye - one that produces zero side effects - can be quite elusive. New research ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...