The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

HOUSTON Bristol-Myers Squibb Company unveiled both a scientific achievement and a patent strategy that, if used by other drug companies, could delay introduction of cheaper generic versions of ...

The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...

One of the most comprehensive ocular pharmacokinetic studies including metabolism so far provides valuable information for ocular drug development. Severe visual illnesses are increasing in our ...

Bioactive metabolites extracted from natural resources serve as drugs for the treatment of various diseases. A new review article published in the Journal of Biotechnology has provided information on ...

Gut bacteria may interact with therapeutic drugs in ways that can result in both reduced microbial fitness or reduced drug efficacy. For example, drugs may be inactivated or otherwise chemically ...

A perceived notion of reactive metabolite formation as a standalone predictor of toxicity risks may be over exaggerated and that other factors such as body burden of the reactive moiety may be a ...

If you have a scheduled drug test coming up, it is important to avoid foods that might falsely trigger a positive. These are some of the foods, ingredients, and beverages that can cause you to fail a ...

Please provide your email address to receive an email when new articles are posted on . An oral medication that targets metabolites in the gut is both safe and well-tolerated for adolescents with ...