Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT. Using tiny, engineered livers derived from cells from human ...

The same GLP-1 medications reshaping weight loss have been linked to lower rates of depression and anxiety, adding to a ...

Advanced melanoma treatment has a familiar failure point: tumors that respond well to targeted drugs at first, then find a ...

Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit NAP.edu/10766 to get more information about this ...

In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality In a ...

Some people use the terms “drug tolerance,” “addiction,” and “dependence” interchangeably, but they do not mean the same thing. Drug tolerance occurs when the body or brain does not respond to a drug ...

Even the best products won't meet expectations if they are packed poorly - packaging matters. The same goes for drug delivery. Osaka Metropolitan University researchers have uncovered the critical ...

Gut microbiota shape drug metabolism through direct and indirect mechanisms that affect therapeutic outcomes. Microbial enzymes can catalyse the biotransformation of xenobiotics, altering ...

Researchers discovered that more than 300 liver genes are under circadian control: Circadian variations affect how much of a drug is available and how effectively the body can break it down. Giving ...

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of ...