T-box riboswitches regulate gene expression by sensing tRNA aminoacylation status, but their dynamic mechanisms remain elusive. Here, we present single-molecule FRET studies of a full-length ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
Base editing and prime editing can be used to permanently fix pathogenic variants but require the development of a distinct drug to correct each pathogenic variant. Suppressor transfer RNAs (sup-tRNAs ...
Coronaviruses pose a major global health threat due to their ability to cross species barriers and establish infections in humans 1. These zoonotic transmissions, exemplified by the COVID-19 pandemic, ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
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