Maintenance of genome integrity is vital for cells and organisms. Cells have evolved a prompt set of actions, the DNA damage response (DDR), to react to any discontinuity in their nuclear DNA. DNA ...

Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the ...

A special form of RNA called extra-coding RNA, or ecRNA, controls the careful targeting to add or remove methyl groups to chromosomal DNA of the adult neuron. The ecRNAs are fundamental regulators of ...

This output from a sequencing machine includes the University of Washington team’s exploit, which is being sequenced with a number of unrelated strands. Each dot represents one strand of DNA in a ...

In eukaryotes, DNA double-strand breaks (DSBs), one of the most harmful types of DNA damage, are repaired by homologous repair (HR) and nonhomologous end-joining (NHEJ). Surprisingly, in cells ...

BOSTON, Mass. — What if all the information on the internet could be stored in a drop of liquid the size of a quarter? What if billions of copies of that information could be made in minutes? And what ...

Henry M. Kronenberg, Barbara E. McDevitt, Joseph A. Majzoub, Jeremy Nathans, Phillip A. Sharp, John T. Potts and Alexander Rich Proceedings of the National Academy of Sciences of the United States of ...