Psilocybin, ketamine, and MDMA are psychoactive compounds that exert behavioral effects with distinguishable but also overlapping features. The growing interest in using these compounds as ...
G protein-coupled receptors (GPCRs) are a prominent class of therapeutic targets for which structure-based drug discovery (SBDD) has traditionally been challenging to apply. However, recent artificial ...
On a morning in November 2023 Eamon Keenan, a psychiatrist who runs addiction services at Ireland’s state-funded health-care provider, received a worrying phone call. “People in homeless accommodation ...
What can the shape of the nucleolus tell us about a cell’s response to drugs? Researchers use advanced microscopy techniques ...
Moving cannabis to a category of drugs that includes some common medicines will have implications for research, businesses and patients. By Jan Hoffman President Trump on Thursday ordered cannabis to ...
Today’s illicit chemists can quickly cook up drugs far more dangerous than fentanyl. By Jonathan Corum and Matt Richtel Illicit labs are creating new synthetic drugs at breakneck speed. Dangerous, ...
It's known as a party drug of choice: cheap, readily available, and a “really good intensifier”. But ketamine wasn't designed for recreational use - it's a powerful anaesthetic, with a nasty dark side ...