Stefan Fröhling, M.D., and Hartmut Döhner, M.D. The cause of chromosomal abnormalities remains poorly understood. Studies of various types of leukemia have shown that certain environmental and ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...

Using a new technique, long-read sequencing, that allows DNA to be analyzed in much greater detail than before, a team of Swedish clinicians and researchers has discovered an unexpected complexity in ...

Researchers are investigating the potential of CRISPR in relation to Down syndrome.

The American College of Medical Genetics and Genomics (ACMG) has released a new Evidence-Based Clinical Practice Guideline (EBG), "Noninvasive prenatal screening for fetal chromosome abnormalities in ...

An AI tool identifies cells that can shed light on the earliest origins of cancer through a game of molecular ‘laser tag’. The human body relies on precise genetic instructions to function, and cancer ...

Through their method, the researchers discovered that chromosomal abnormalities in aging eggs therefore result from a combination of failures, ranging from a drop in REC8 levels to the gradual ...