Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions. Japanese researchers have revealed how changes in chromatin accessibility—how DNA ...