The centrosome has been a subject of fascination for cell biologists for at least a century. It is at the centre of the cell and is the structure on which microtubules organize themselves both during ...
Centrosomes, which are composed of two centrioles and pericentriolar material, serve as the main microtubule-organizing centre in animal cells. They duplicate once per cell cycle so that each daughter ...
Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...
The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that ...
Scientists have unraveled how the cell replication process destabilizes when it has more, or less, than a pair of chromosome sets, each of which is called a genome -- a major step toward understanding ...
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8+ T cell division for the generation of memory precursor cells.